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Excipients used in solid dosage forms, excipients used in formulation of tablets and excipients of liquid dosage form are very important to reduce or eliminate the damage to liposomes caused by the lyophilization process. Dehydration of liposomes can cause the transition from liquid crystal state to gel state of phospholipids, and rehydration of dried liposomes can also be acco***nied by transition from gel state to liquid crystal state, both of which can cause leakage of liposome contents, particle size increasing and the transition from single-chamber to multi-chambers. Therefore, it is very important to select a suitable lyoprotectant to reduce or eliminate the damage to liposomes caused by the lyophilization process. AVT is a reliable supplier of excipients used in semi solid dosage forms and excipients for liquid dosage form.
TYPES OF PROTECTIVE AGENTS (FOR LIPOSOMES)
D(+)-Trehalose Dihydrate (For Injection) CAS NO 6138 23 4
£¨AVT brand trehalose dihydrate (for injection) is commonly used as lyoprotectants, besides it is also stabilizer and cryoprotectant for lipid nanoparticles and mRNA. |
| Company: |
AVT (Shanghai) Pharmaceutical Tech Co., Ltd
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avt com |
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Room A, 27th Floor, Huadu Mansion, No.838, Zhangyang Road, Pudong District |
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+86-021-61060972 |
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